SHAp (SofSera Hydroxyapatite)

[dt_fancy_title title=”SHAp (SofSera Hydroxyapatite)” title_align=”left” title_size=”h2″ title_color=”accent” separator_style=”disabled”]
[dt_fancy_title title=”Application of Functional Cosmetics” title_align=”left” title_size=”h4″ title_color=”custom” separator_style=”disabled” custom_title_color=”#a81313″]

shap_1

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[dt_fancy_title title=”Mechanism of SHAp Action” title_align=”left” title_size=”h4″ title_color=”custom” separator_style=”disabled” custom_title_color=”#a81313″]

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  • Fibroblast: Reacting with hydroxyapatite and infiltrating by holding out the microspike.
  • Hydroxyapatite: dark-dyed.
[dt_fancy_title title=”Extracellular Matrix Observation” title_align=”left” title_size=”h4″ title_color=”custom” separator_style=”disabled” custom_title_color=”#a81313″]

On the SHAp compounded sheet, fibronectin is produced abundantly, remodeling of extracellular matrix occurred remarkably.

shap_3Click image above to enlarge

National Cerebral and Cardiovascular Center, Department of Biomedical Engineering: Tsutomu Furuzono.

University of Tsukuba, Life and Environmental Sciences: Oh’s group.

[dt_fancy_title title=”Extracellular Matrix Observation” title_align=”left” title_size=”h4″ title_color=”custom” separator_style=”disabled” custom_title_color=”#a81313″]

On the SHAp compounded sheet, fibronectin is produced abundantly, remodeling of extracellular matrix occurred remarkably.

shap_4Click image above to enlarge

National Cerebral and Cardiovascular Center, Department of Biomedical Engineering: Tsutomu Furuzono.

University of Tsukuba, Life and Environmental Sciences: Oh’s group.

[dt_fancy_title title=”Test for accelerated production of type 1 collagen by fibroblast” title_align=”left” title_size=”h5″ title_color=”custom” separator_style=”disabled” custom_title_color=”#a81313″]

shap_5Click image above to enlarge

[Method]

Cultivating fibroblast of normal human in culture media including 0.5% FBS-DMEM for 24 hours, and determining quantity of collagen in the culture media. 

[Testing Agency]

Nikoderm Research Inc.

Collagen was increased without any change in the amount of protein