SHAp (SofSera Hydroxyapatite)

SHAp (SofSera Hydroxyapatite)
Application of Functional Cosmetics

shap_1

Click image above to enlarge

Mechanism of SHAp Action

shap_2Click image above to enlarge

  • Fibroblast: Reacting with hydroxyapatite and infiltrating by holding out the microspike.
  • Hydroxyapatite: dark-dyed.
Extracellular Matrix Observation

On the SHAp compounded sheet, fibronectin is produced abundantly, remodeling of extracellular matrix occurred remarkably.

shap_3Click image above to enlarge

National Cerebral and Cardiovascular Center, Department of Biomedical Engineering: Tsutomu Furuzono.

University of Tsukuba, Life and Environmental Sciences: Oh’s group.

Extracellular Matrix Observation

On the SHAp compounded sheet, fibronectin is produced abundantly, remodeling of extracellular matrix occurred remarkably.

shap_4Click image above to enlarge

National Cerebral and Cardiovascular Center, Department of Biomedical Engineering: Tsutomu Furuzono.

University of Tsukuba, Life and Environmental Sciences: Oh’s group.

Test for accelerated production of type 1 collagen by fibroblast

shap_5Click image above to enlarge

[Method]

Cultivating fibroblast of normal human in culture media including 0.5% FBS-DMEM for 24 hours, and determining quantity of collagen in the culture media. 

[Testing Agency]

Nikoderm Research Inc.

Collagen was increased without any change in the amount of protein